Effects of Aging on Amplitude-Modulated Encoding in Primary Auditory Cortex

Temporal envelope processing is critical for speech comprehension, which is known to be affected by normal aging. While the macaque is an excellent animal model for human cerebral cortical function, few studies have investigated neural processing in the auditory cortex of aged non-human primates. In this podcast, Editor-in-Chief Bill Yates (University of Pittsburgh), Associate Editor Conny Kopp-Scheinpflug (Ludwig-Maximilians-Universität München), content expert Robert Frisina (University of South Florida) join lead author Jacqueline Overton (UC Davis Center for Neuroscience) in an engaging discussion about age-related changes in the spiking activity of neurons in primary auditory cortex of aged macaque monkeys. What is the role and importance of rate and temporal codes in representing dynamic auditory stimuli? Listen and find out.

Effects of aging on the response of single neurons to amplitude-modulated noise in primary auditory cortex of rhesus macaque
Jacqueline A. Overton, Gregg H. Recanzone
Journal of Neurophysiology, published June 3, 2016. DOI: 10.1152/jn.01098.2015.