Episodes
Friday Sep 20, 2024
JNP Micro Podcasts: Beadex is required in Neurons
Friday Sep 20, 2024
Friday Sep 20, 2024
In this podcast coauthor Kripa Chitre discusses the recently published article titled "Beadex, the Drosophila LIM only protein, is required for the growth of the larval neuromuscular junction." A novel role for Beadex (Bx) regulates the larval neuromuscular junction (NMJ) structure and function in a tissue-specific manner. Bx is expressed in a subset of Toll-6-expressing neurons and is involved in regulating synaptic span and physiology, possibly through its negative interaction with Highwire (Hiw). The findings of this study provide insights into the molecular mechanisms underlying NMJ development and function and warrant further investigation to understand the role of Bx in these processes fully.
Journal of Neurophysiology 2024 132:2, 418-432