Pharmacological modulation of the M-current shapes locomotor function in developing zebrafish

In this episode, coauthors Stephanie Gaudreau and Tuan Bui discuss their recently published research, “Pharmacological modulation of the M-current shapes locomotor function in developing zebrafish.” For the first time, they show that the M-current influences escape responses and swimming in larval zebrafish, with experiments in isolated spinal preparations revealing its presence in spinal circuits.

Pharmacological modulation of the M-current shapes locomotor function in developing zebrafish

Stephanie F. Gaudreau and Tuan V. Bui

Journal of Neurophysiology 2025 133:6, 1795-1806