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![JNP Micro Podcasts: Inhibitory Synaptic Transmission in the Kölliker-Fuse of Rett Syndrome mice](https://pbcdn1.podbean.com/imglogo/ep-logo/pbblog946291/jn-00327-2023r01_300x300.png)
Monday Mar 11, 2024
Monday Mar 11, 2024
In this episode of JNP's micro podcasts, Jessica R. Whitaker-Fornek of the University of Michigan Medical School discusses the recently published research titled "Inhibitory synaptic transmission is impaired in the Kölliker-Fuse of male, but not female, Rett syndrome mice."
NEW & NOTEWORTHY Kölliker-Fuse (KF) neurons in acute brain slices from male Rett syndrome (RTT) mice receive reduced inhibitory synaptic inputs compared with wild-type littermates. In female RTT mice, inhibitory transmission was not different in KF neurons compared with controls. The results from this study show that sex-specific alterations in synaptic transmission occur in the KF of RTT mice.
Journal of Neurophysiology 2023 130:6, 1578-1587